Tissue Plasminogen Activator Market - Global Industry Analysis, Size, Share, Growth, Trends, and Forecast 2018 - 2028
Advances in recombinant technology have enabled researchers to utilize the thrombolytic activity of tissue plasminogen activator (tPA) in synthetic products. The tissue plasminogen activator market has thus witnessed a growing array of recombinant tissue plasminogen activators with useful pharmacokinetic and pharmacodynamic properties. Key products comprise alteplase, reteplase, and tenecteplase. Numerous regulatory agencies, particularly, the U.S. FDA has highlighted the therapeutic potential of these in a range of diseases, notably including ischemic stroke, myocardial infarction, and thrombolysis. Relentless focus on improving the half-life of some of these recombinant tPAs is propelling advances in the tPA market over the past few years.
Tissue plasminogen activators are usually administered through regional intra-arterial routes or intravenously. Recent body of clinical studies have shown that tPAs can be a risk marker for cardiovascular disease. Growing in vivo studies on fibrinolytic system is also boosting the market. tPA products have in recent years grown in popularity for the treatment of acute ischemic stroke (AIS). Several studies on reversing tPA toxicity are expected to boost the tissue plasminogen activator market.
A substantial proportion of the worldwide populations suffer from stroke at some point in their lives. The numbers of people who die due to strokes are also bewildering, especially in developed countries such as the U.S. In addition, the growing prevalence of cardiovascular diseases around the world has been putting large pressure on the quality of patient care. All these factors have catalyzed the demands in the tPA market. However, several contraindications need to be taken in consideration while using tPA in therapies. Adverse reactions commonly include cardiogenic shock, hypotension, muscle pain, allergic reaction, and intracranial hemorrhage.
Nevertheless, the vast clinical prospect of recombinant tPAs has put pressure on healthcare teams world over to circumvent these concerns. To this end, the healthcare team comprising nurses, pharmacists, and physicians along with the research fraternity, have been making concerted efforts. Meanwhile, continuous and rapid advances in discovering novel thrombolytic therapies are expected to impart momentum to the future stride in the market. The utilization of tPA in early reperfusion therapy as a life-saving therapy will likely expand the potential of the tissue plasminogen activator market.
Over the past few years, the health care industry has witnessed rapid advances in evaluating various treatment modalities for ischemic strokes and consequently increasing the survival rates in patients. This has opened new windows of opportunities in the tissue plasminogen activator market. Several of these advances have been fueled by growing expertise and knowledge of emergency medical services (EMS) providers. Numerous comprehensive stroke centers are expected to benefit from such knowledge. A recent study by a team of researchers at the U.S. aimed to assess the preparedness of EMS in managing stroke patients in prehospital care settings. Such focus will help expand the clinical prospects of the application of tPA, opening new avenues in the tissue plasminogen activator market.
On the regional front, North America has been showing considerable prospects in the tissue plasminogen activator market. A large degree of the growth is propelled by recent advances in health care industry toward the management of patients with strokes and numerous cardiovascular diseases. Extensive research over the recent years in improving the biological activity and efficacy of tPA has also expanded the potential of the regional market.
Meanwhile, among other key markets, Asia Pacific is worth mentioning. Their contribution to the global market is likely to grow substantially in the not-so-distant future.
The study presents a granular assessment and quantitative evaluation of:
The region-wise assessment includes market dynamics in:
The study is prepared with the help of an extensive primary and secondary research. Primary research includes but not limited to interactions, interviews, surveys, and events. Opinions of policy makers and industry experts are carefully integrated into the insights to complement primary research. Volumes of secondary data gleaned through renowned paid sources, annual statements, reputed journals, and government documents offer insights into current dynamics and key evolution trajectories the market is likely to assume. The research employs various industry-wide analytics methods and well-established methodologies to ascertain the attractiveness of key segments. Further, it evaluates the lucrativeness of key regions and factors underlying their maturity. The insights notably include a detailed analysis of forces behind vendor differentiation and offers insight into investment-decision making by prominent players.
The report strives to enlighten businesses and industry stakeholders on multiple facets of the growth dynamic of the market, the key of which include answers to:
Note: Utmost care has invariably been taken to present data and arrive at statistics at all the TMR Research reports. Meanwhile, some recent developments and new industry trends may take time to be included in the reports.
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