In Vivo Toxicology market Global Industry Analysis, Size, Share, Growth, Trends, and Forecast, 2020 - 2030

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In Vivo Toxicology market Global Industry Analysis, Size, Share, Growth, Trends, and Forecast, 2020 - 2030

Status : May, 2021 | Healthcare IT

Report Digest


In vivo toxicology is the study of toxic effects of chemical substances performed on living organisms, e.g. laboratory animal. Researchers conduct in vivo testing for determining the reduction in the toxic effects of reduced risk products. Mostly, rodents, mice and rats are used as non-human living organisms for in vivo study. Increasing research activities, innovations in animal models are the key growth prospects.

Study of In Vivo Toxicology for Cancer Phenotypes

In vivo models integrating both cardiovascular and cancer phenotypes allow for the study of on and off target mechanisms of toxicity arising from these agents. Zebra fish as the optimal in vivo model is utilized to screen for cardiotoxicity in a high throughput manner while analysing the work of cardiotoxicity pathways on the cancer therapy’s antitumour effect. As zebrafish and human have high degree of genetic conservation, in vivo toxicology study proves to be a good option for research. Thus, growing the demand in vivo toxicology and eventually driving the growth of market.    

Growing Research Activities

Increasing number of pharma companies are focussing on research and development activities owing to growing competition in the health care sector. To provide the best research and accurate analysis, the focus on research activities is must for these companies. Investments in the pharma sector have been increased in developing as well as developed regions for precise research to increase the use of in vivo toxicology.    

Regulations against Death of Animals may inhibit the Growth

 PETA and other animal welfare agencies have been vocalising against animal abuse for research purpose since long. Several arguments have been made by the activists that it is morally wrong to let animal suffer because of human requirements. UK’s National Centre have prepared the study for Refinement, Replacement and Reduction of animal use in in vivo toxicology testing and many other countries are adopting the plan too. Alternatives such as in vitro testing, ex vivo testing and in silico testing are utilized. In vitro testing involves performing experiments outside the living organism in a controlled environment such as in test tube or petri dish. Such testing help reduce animal requirement and may inhibit the adoption of in vivo toxicology during the forecast period.

Competitive Landscape

The prominent players include Envigo (US), Thermo Fisher Scientific (US), Waters Corporation (US), Agilent Technologies (US), Taconic Biosciences, Inc. (US), Shimadzu Corporation (Japan), Bruker Corporation (US), GE Healthcare (US), Bio-Rad Laboratories (US), Genoway (France), Polygene (Switzerland), Merck KGaA (Germany), Danaher Corporation (US), The Jackson Laboratory (US), Perkin Elmer (US), etc.

Genoway, a leader in developing genetically modified research models has partnered with Merck, a leading Science and Technology Company in Jan 2020 to commercialize the development and use of all other animal cell models for the internal research for its customers. Merck is now the leading provider of foundational CRISPR IP, according to the COO of genoway.

Waters Corporation in September 2020 announced the inauguration of their new research lab, Immerse Cambridge located at the centre of Kendall Square. Immerse Cambridge is a collaborative space for research to escalate and co-create towards the next generation of scientific advancements.

In March 2020, Danaher Corporation announced the acquisition of the Biopharma Business from GE Health care’s Life Sciences division. The business will be called Cytiva and will be a standalone operating company in the company’s Life Sciences Segment.

 Altogen Labs, a GLP compliant contract research organisation in 2020 have introduced a research lab offers in vivo xenograft efficacy studies and toxicology services designed to escalate preclinical research and drug development.  

Regional outlook

The global demand of in vivo toxicology depends on many factors including growth in research and development activities, growing expenditure by health care companies, etc. Spending on health care is reaching heights globally and the spending is likely to reach up to $10 trillion by 2022.

North America is expected to hold the dominant share regarding the growth of in vivo toxicology. Health care sector in US comprise 18% of GDP. In 2019, United States spent about $11,100 per person on health care which is the highest in the world. Furthermore, spending on research and development by major players in the market has been a key growth prospect. 

China in Asia Pacific is also moving rapidly owing to increasing investments in research and development sector. China R&D investments increased by over 15% in 2018 as per aaas.org, with Korea being the number second largest investor in research and development activities. Increased focus of government organizations to promote toxicology remains the primary reason for the growth of in vivo toxicology. According to ibef.org, private sector is acting as a vibrating force for Indian health care market and accounts for almost 74% of country total health care.

In 2019, European Union spent over 306 million Euros on research and development which accounts for 2.19% of GDP making it significantly growing region in in vivo toxicology market. However, government policies and ban on production and sale of animal tested cosmetic products and other anti-animal testing laws is restraining the European region to grow in vivo toxicology market.

Segmentation

By Product

  • Instruments
  • Consumables
  • Animal Models
  • Reagents and kits

By Test Type

  • Acute
  • Sub-acute
  • Sub chronic
  • Chronic test type

By Testing Facility

  • Outsourced testing facility
  • In-house testing facility

By Toxicity End Point

  • Innumotoxicity
  • System toxicity
  • Carcinogenicity
  • Developmental & reproductive toxicity
  • Genotoxicty

By End User

  • Pharmaceutical companies
  • Contract Research Organisations
  • Academic and Research Institute

By Company Type

  • Tier 1 Pharmaceutical Companies
  • Tier 2 Pharmaceutical Companies
  • Tier 3 Pharmaceutical Companies

By Region

  • North America
  • Europe
  • Asia Pacific
  • Latin America
  • Middle East and Africa

Key Questions Answered

  • Who are the leading players in in vivo toxicology market?

    Waters Corporation (US), Agilent Technologies (US), Taconic Biosciences, Inc. (US), Shimadzu Corporation (Japan), Bruker Corporation (US), GE Healthcare (US), Bio-Rad Laboratories (US), etc.

  • Which test types are there for in vivo toxicology?

    Acute, sub-acute, sub chronic, chronic test type.

  • Which testing facility is expected to grow during the forecast period?

    Outsourced testing facilities segment accounts for holding the largest market share.

  • Which test type is expected to hold the largest share?

    Chronic test type attributing to increased research on drugs for anti-cancer, anti-chronic diseases.

  • Which region is likely to dominate the adoption of in vivo toxicology?

    North America is expected to hold the largest share in the market.

This study provides a particularized anatomy according to the L.E.A.P mechanism

  • Latest trends and cardinal growth prospects
  • Existing and future insights in growth
  • Ascensions in technology
  • Pain points

The regional analysis offers market assays across:

  • North America
  • Asia Pacific
  • Europe
  • Latin America
  • The Middle East and Africa

The study, prepared through the L.E.A.P mechanism adds a dimension of infallibility and assures precise information on all the growth dynamics.

Latest Trends and Cardinal Growth Prospects

The study assists in burnishing the knowledge of the stakeholder in terms of the emerging trends. The study provides an expansive coverage on the latest developments and novel profit-yielding sources that augur well with the market. A dedicated and determined team of experts conduct an out-and-out research on diverse aspects to offer ultimate breakthroughs in the market.

Existing and Future Insights in Growth

The interfusion of ubiquitous primary and secondary research through modern tools invites perfection and accuracy in every aspect. Primary research is circumspectly conducted through exhaustive interactions and interviews of experts. These valuable opinions are then neatly inducted in the report to allow the stakeholder for reaping the benefits. A treasure of secondary data is extracted via famed paid sources, yearly estimates and statements, renowned journals, and government documents. These sources assist in creating a robust database comprising existing and subsequent growth dynamics.

Ascensions in Technology

Diverse technological advancements and cutting-edge innovations in the market have been covered in this study to assist the stakeholder in research and development activities. Recent upgrades have also been added in the study, thus helping the stakeholder to paint the strokes of growth on the canvas of the market.

Pain Points

The study presents a plethora of challenges and obstacles that can hinder the growth of the market to allow the stakeholder to prepare their strategies accordingly.

The world ushered in the new decade with the shadow of the COVID-19 pandemic. The outbreak has damaged the growth prospects of several businesses and has crippled the entire economy. The study is in tandem with the changing dynamics of the market due to the SARS-CoV-2 outbreak. The study focuses on the coronavirus pandemic and analyses every aspect that impacts the growth positively or negatively.

An aerial perspective of the regions covered in this study enables the stakeholder to design strategies accordingly. The 360-degree assessment of every aspect associated with growth offers information on a rainbow of growth opportunities available across the market.

The exhaustive study motivates the stakeholder to take the 'LEAP' of faith and achieve success!

This report is the key to questions such as:

What are the prominent factors that will help in reshaping the market growth?

Which trends have the potential to bring expansive growth for the market?

What are the necessary strategies to overcome the ill-effects of the COVID-19 pandemic?

Which regions will emerge as champion growth contributors for the market?

Which aspects will serve as game-changers for the market?

What are the latest innovations in the market?

Which factors will hinder the growth of the market?