Humanized Mouse Model Market - Global Industry Analysis, Size, Share, Trends, Analysis, Growth, and Forecast 2017 - 2025

  • Single User License $3500

Humanized Mouse Model Market - Global Industry Analysis, Size, Share, Trends, Analysis, Growth, and Forecast 2017 - 2025

Status : February, 2023 | Biotechnology

Report Digest

Global Humanized Mouse Model Market: Snapshot

The global humanized mouse model market is estimated to gain a valuation of US$ 188.57 Mn by 2027. Thus, the market for humanized mouse model is projected to expand at a CAGR of 9.54% during the forecast period of 2020 to 2027. The total valuation of the humanized mouse model market was US$ 95.72 Mn in 2019.

Humanized mouse models are used in by a wide range of end-users such as contract research organizations, academic & research institutions, and companies operating in the biotechnology and pharmaceutical industry.

Over the period of past few years, there has been a rise in the demand for personalized medicines for different health disorders. Hence, major biotechnology and pharmaceutical companies across the globe are collaborating with scientists in order to increase research activities and fulfil the current market demand. This factor is resulting into the rapid expansion of the global humanized mouse model market.

The products from the global humanized mouse model market find application in different segments of the healthcare industry such as the neuroscience, immunology and infectious diseases, haematopoiesis, toxicology, and oncology. In the recent years, numerous research centers are increasing the use of humanized mouse models in the discovery of different therapeutics and innovative vaccines. This factor is estimated to generate lucrative prospects in the global humanized mouse model market in the upcoming years.

Government authorities as well as private sectors from across the globe are providing financial support for different researches intended for the development of advanced solutions for several chronic diseases such as varied cancer types. Hence, rise in the number of researches concentrated on the development of innovative and effectual solutions for the treatment of cancer are resulting into promising business prospects for companies operating in the global humanized mouse model market.

The pharmaceutical industry has been experiencing a consistent surge in the past decade, owing to rising prevalence of a number diseases, and biotechnology promises to revolutionize the field going forward. This surge is quite evident on the global humanized mouse model market too, which is based on humanizing mice with a short strand of human DNA, tissue, tumor, or microbiome. The mice that are humanized make for a highly useful model to study genetics, and ultimately leading to the development of new drugs. 

Some of the leading companies in this market are aggressively investing on research and development as well as pursuing alliances and acquisitions to maintain their stronghold. For instance, Horizon Discover Group plc. recently announced the signing of a Master Services Agreement (MSA) with three pharmaceutical companies in order to expand their drug discover efforts and attain full suite of services from their organization. Services included under the MSA are: target identification and validation screening, customer line engineering, cell-based assay services, and drug combination screening. On the other hand, another prominent name in this industry, The Jackson Laboratory, has developed humanized NSG (hu-NSG) and NSG-SGM3 mouse models as tools to study cancer, infectious and inflammatory disease, and hematopoiesis. Taconic Biosciences, Inc., another key vendor in the global humanized mouse model market, offer nearly 4,500 genetically engineered mice and rats with health status such as germ-free (GF), defined flora (DF), excluded flora (EF), restricted flora (RF), and murine pathogen free (MPF). Type of animal offered by Taconic Biosciences include conditional knock out, constitutive knock out, double knock out, congenic,  hybrid, inbred, microinjected, and outbred.

Global Humanized Mouse Model Market: Overview 

A humanized mouse is referred to as a mouse transmitting functioning human organs, tissues, cells, and genes. Humanized mice are basically employed in medical and biological therapeutics as animal models. Immunodeficient mouse are often act as recipients of tissues or human cells, as they can easily receive heterologous cells because of lack of immunity in the host. Conventionally, the severe combined immunodeficiency (SCID) mouse and the nude mouse have been employed for the aforesaid purpose. However, recently the NSG and NOG mouse have been exposed to engraft human tissues and cells more effectively than any other model variant. Such models of humanized mouse might be employed for modelling the human immune system in situations of pathology and health, and also is likely to enable the evaluation of therapeutic candidates in an in vivo setting which is relevant to human psychology. 

CD34 mouse models are employed as in vivo platforms for the purpose of examining the safety and efficiency of possible new drugs that can moderate the immune system. Moreover, they are also used for long-term research in the fields of infectious disease, immuno-oncology, and graft versus host disease. Therefore, the rising application fields of CD34 models are anticipated to intensify the demand for these humanized mouse models over the coming years. 

The market intelligence publication delves into the possible growth opportunities for the global humanized mouse market and the chronological growth of the market throughout the forecast period. It also uniquely provisions required data related to facers such as dynamics influencing the progress in all possible retrospective manner. Several ubiquitous and non-ubiquitous trends have also been mentioned in the study. An outlook of extensive nature keeping in mind the Porter’s five forces analysis has been provided to make the vendor landscape transparent to the reader. The report further reaches out to point out accomplishments related to R&D, acquisitions, mergers, and crucial partnerships and verifications. The companies in limelight have been analyzed on market shares, products, and key strategies. 

Global Humanized Mouse Model Market: Trends and Opportunities 

The progress of the global humanized mouse model market can be credited to the incessant support by the governments across the globe for research projects in the form of grants and investments, a significant upsurge in the amount of research projects concerning humanized mouse models, high R&D activities by biotechnology and pharmaceutical companies, and the mounting adoption of personalized medicines. Based on type, the humanized mouse model market can be classified into cell-based and genetic humanized mouse model. The segment of genetic models is projected to hold for the leading share in the global humanized mouse model market until the end of the forecast period. The segment of cell-based models is likely to expand at a strong CAGR from 2017 to 2025 due to the cumulating number of applications of cell-based humanized mouse models. The cell-based mouse model segment can be further classified into PBMC, BLT humanized mouse, and CD34. In 2016, CD34 model held the dominating share in the global cell-based humanized mouse model market and also exhibited a strong CAGR.

Global Humanized Mouse Model Market: Regional Outlook 

Owing to the significant rise in expenditure on R&D and biomedical research by several leading pharmaceutical companies, North America is expected to emerge as prominent region in the global humanized mouse model market in the near future. Asia Pacific is also expected to exhibit strong growth due to the growing focus on personalized medicines in China and rising investment by the governments of various countries in the region in the development of the life science sector and regenerative medicines. 

Global Humanized Mouse Model Market: Vendor Landscape 

The leading companies in the market include Horizon Discovery Group PLC, genOway S.A., Axenis S.A.S, ingenious targeting laboratory, HuMurine Technologies, Inc., Harbour Antibodies BV, and The Jackson Laboratory.

The reports at TMR Research provide qualitative solutions that break the barriers of doubt or uncertainties when the stakeholders plan to expand their growth reach. The researchers compile the necessary information that enlightens the CXOs about the current growth opportunities in a specific market and enables them to make the most of the opportunities.

TMR Research is a leader in developing well-researched reports. The expertise of the researchers at TMR Research makes the report stand out from others. TMR Research reports help the stakeholders and CXOs make impactful decisions through a unique blend of innovation and analytical thinking. The use of innovation and analytical thinking while structuring a report assures complete and ideal information of the current status of the market to the stakeholders.

TMR Research has rich experience in developing state-of-the-art reports for a wide array of markets and sectors. The brilliance of the experts at TMR Research and their alacrity to conduct thorough research and create phenomenal reports makes TMR Research better than others.

5-Point Growth Formula

The 5-point growth formula developed by TMR Research provides an insight to the stakeholders and CXOs about the current situation in the market. The growth formula makes the report a perfect companion for the stakeholders and CXOs.

The 5-point growth formula includes the following points:

  • Current and Future Threats
  • Accurate Trend Analysis
  • Regional Assessment
  • Industrial Analogy
  • COVID-19 Impact

Current and Future Threats

Along with studying the opportunities necessary for growth, threats are also an important aspect to look upon for the companies and stakeholders in a specific sector. TMR Research studies every negative aspect that will hinder the growth of a specific area of business and includes it in the report. The stakeholders and CXOs will have the benefit of assessing the threat and take the necessary steps to prevent the hindrance caused due to the threats.

Accurate Trend Analysis

Keeping up with the latest trends is crucial in any business or sector. While stakeholders are aware of the trends that are on the surface, TMR Researchers find trends that are deeply entrenched in the particular market or sector. The reports are constantly updated with the latest trends so that the stakeholders and CXOs can derive benefits from the trends and generate good revenues.

Regional Assessment

Demography forms an important part of the growth pattern of all the markets. Diving deep into the demographics enables maximum output from specific areas. The TMR Research team assesses every region and picks out the vital points that have a large impact on the growth of a market.

Industrial Analogy

The analysts at TMR Research conduct an all-round analysis on the competitive landscape of the market. The observations recorded by the analysts are added to the reports so that every stakeholder gets a glimpse of the competitive scenario and frame their business plans according to the situation.

COVID-19 Impact

The COVID-19 outbreak has changed the growth projections of numerous sectors and businesses. The analysts at TMR Research have conducted a conscientious survey on the markets after the pandemic struck. The analysts have put forth their brilliant and well-researched opinions in the report. The opinions will help the stakeholders to plan their strategy accordingly.

The reports offer answers to the top 7 questions that revolve around the growth of the market

  • What are the diverse growth parameters influencing the market?
  • Which regions will contribute largely to the growth of the market
  • What are the recent innovations and technological advancements in the market?
  • What are the emerging trends across the market?
  • How has COVID-19 affected the market?
  • What will be the post-pandemic scenario of the market?
  • What are the major threats that will dent the growth prospects of the market?