Biotechnology Research

Also known as genome editing with engineered nucleases (GEEN), genome editing is a method of altering DNA within a cell in a safe manner. The technique is also used for removing, adding, or modifying DNA in the genome. 

Based on products and services, the global high-resolution melting analysis market can be segmented into software and services, consumables and reagents, and instruments. In terms of application, it can be segmented into epigenetics, pathogen identification, species identification, mutation scanning, and SNP genotyping.

In biomanufacturing, high throughout process development tools and technology platforms could be engaged for a simpler and faster development of downstream chromatography processes. High throughput process development is expected to address the concern about reducing development time and designing scalable and robust processes by increasing process knowledge.

High-content screening (HCS) refers to a technique used in biological research and drug discovery to discover substances such as peptides, small molecules, or RNAi that change the phenotype of a cell as desired. Phenotypic changes may include increase or decrease in the production of cellular components such as protein and/or alterations in the visual appearance of the cell.

The global biobanks market owes its conception to the rising need for replacement organs and the steady advancement in the replacement and transfusion technologies regarding a number of bodily substances. Though the technology and need to store organs and other bio-entities had been available for a long time, the global biobanks market took on a more important role in the healthcare sector following the increasing research in genomics.

The growth of microbiology testing market is primarily driven by the recent technological advancements that have not only made the tests faster, they are more accurate now as well as affordable for a larger consumer base. In the medical field, microbiology has always been a branch of enthusiasm that has promised a lot as far as prevention, diagnosis, and treatment of infectious diseases is concerned. 

Cell culture protein surface coatings help in improving cell attachment, growth, and differentiation. They facilitate consistent performance in various cell-based assays and in-vitro culture by improving cell adhesion. A variety of adhesion proteins and other biological materials derived from various sources are being used to enhance performance in cell culture, especially in cell lines that are hard to attach, such as transfected cells.

Filters are applied in many stages during the production of small molecule drugs, also referred to as active pharmaceutical ingredients (API). They remove or lessen the particles and bacteria in process components. The filters prevent process solutions from getting contaminated when stored in tanks.

Sterility testing finds application for use on raw materials, cell banks, and final drug offerings. However, it is also used for testing various articles, preparations, and substances which are needed to be made sterile as per the laws penned down by the European Pharmacopoeia (EP) and United States Pharmacopoeia (USP). 

The global market for next-generation sequencing is likely to witness a progressive growth in the next few years, thanks to the rising adoption across diverse industries. In addition, several lucrative opportunities in untapped markets and the rise in the number of government initiatives are projected to contribute towards the growth of the market. 

Downstream processing involves the purification and recovery of biosynthetic products especially pharmaceuticals from natural sources. This includes animal or plant tissue including salvageable components that can be recycled and proper treatment and disposal of waste. 

Cannabis testing includes a number of drug test methodologies pertaining to the use of cannabis in sports, medicine, and law. Unlike alcohol, which can be tested using a breathalyser, cannabis testing requires hair analysis, saliva tests, and urinalysis, and is a time consuming process.

Metabolomics refer to the study of the metabolites that exist within an organism, tissue, or a cell. Processes such as interpretation, quantification, identification, and profiling are used for the understanding the entire set of metabolites in a given biological system. 

The trillions of microorganisms living in and on the human body are collectively referred to as human microbiome. These microorganisms include bacteria, protozoa, and fungi. They exhibit a mutualistic relationship and have, therefore, evolved with their human hosts. 

The global market for regenerative medicine market is expected to grow at a significant pace throughout the forecast period. The rising preference of patients for personalized medicines and the advancements in technology are estimated to accelerate the growth of the global regenerative medicine market in the next few years. As a result, this market is likely to witness a healthy growth and attract a large number of players in the next few years.

The global mice model market has been growing at a healthy rate and is likely to continue at the same pace in the near future. A significant rise in the biomedical research in the healthcare and pharmaceutical sector is anticipated to accelerate the growth of the global market in the forecast period.

A biomarker is considered as a biological gene or molecule which is being used extensively across the globe in order to evaluate accurate pharmacologic responses, biological procedures, and pathogenic procedures. In addition, biomarkers are used to check body’s response to a specific treatment for a condition or disease. 

Also called regenerative medicine, stem cell therapy encourages the reparative response of damaged, diseased, or dysfunctional tissue via the use of stem cells and their derivatives. Replacing the practice of organ transplantations, stem cell therapies have eliminated the dependence on availability of donors. Bone marrow transplant is perhaps the most commonly employed stem cell therapy. 

As the frequency of outbreaks of influenza increases globally, the global market for influenza diagnostics is likely to soar. Commonly known as flu, influenza is an illness of the respiratory system caused by viruses. According to the World Health Organization (WHO), influenza is responsible for 250,000 to 500,000 deaths worldwide, making it the second leading disease resulting in mortality, after acquired immune deficiency syndrome (AIDS). 

Clinical laboratory services are a crucial part of the medical and healthcare industry. All sorts of diagnostic tests ranging from genetic analysis to blood tests are accomplished in these clinical laboratories in order to diagnose various diseases. Clinical laboratories provide services and information which help in maximizing the required deliveries in the healthcare system such as test results and diagnostics.

Biotechnology is the employment of organisms and living systems in order to develop products or a technological application that further uses derivatives, living organisms, and biological systems thereof, in order to create or modify processes or products for specific use. Relying on the applications and tools, it at times overlays with related fields such as molecular engineering, biomanufacturing, biomedical engineering, and bioengineering. 

Biopreservation involves maintaining the functionality and integrity of cells, tissues, and organs outside their natural environment for an extended period of storage at different temperatures. For instance, vaccines save 3 million lives every year in the U.S, however, vaccines worth US$ 20 million are wasted each year due to inadequate storage and improper refrigeration. 

In the past few years research and development of CRISPR or clustered regularly interspaced short palindromic repeats has allowed molecular biologists to designs solutions for repairing cells by genome editing. This method allows a change to a specific genome by the introduction of a new function or by correction of a mutation. The exceptional fidelity, simplicity of construction, and low cost has triggered a monumental demand for the several solutions offered by the global CRISPR and CRISPR-associated (Cas) genes market.

Next Generation Sequencing (NGS) is referred to as a non-Sanger based high throughput DNA sequencing technology. This term is specifically used to define several modern and advanced sequencing technologies such as SOLiD sequencing, Proton / PGM sequencing, Roche 454 sequencing, and Illumina (Solexa) sequencing, among others. Billions of strands of DNA can be chained in parallel, substantially yielding more throughput and decreasing the requirement for methods for fragment cloning, often employed Sanger genome sequencing.

Today, complexities involved in genomic research demands a higher level of understanding than what is offered by traditional DNA sequencing methodologies. Next-generation sequencing has become an everyday research tool and filled the gap to cater to these needs.

The international botulinum toxin (BNT) market is gigantically advantaged by the soaring number of applications for different purposes. A recent study has revealed that BNT can be used for benefitting patients with shoulder disorders such as those who undergo rotator cuff surgery. BNT in the form of onabotulinum toxin A (OnabotA) is licensed in several countries such as Korea to help with neurogenic detrusor overactivity (NDO) induced urinary incontinence attributable to multiple sclerosis or spinal cord injury.

The report on clinical laboratory tests market presents a detailed analysis of the key trends, opportunities, challenges, and growth drivers of the market, along with authentic charts and figures. The projected, present, and past leading segments of the global clinical laboratory tests market are examined in the report. The report aims at providing insights into the supply and demand dynamics, competitive landscape, market attractiveness, and key opportunities presented by the regional markets.

The global market for cell sorting has witnessed significant traction in the past few years. Factors such as increasing and easy availability of advanced cell sorters in the global market, rapid technological advancements in product features, and increasing investment and funding are among the key factors to have driven the market in recent times. 

A humanized mouse is referred to as a mouse transmitting functioning human organs, tissues, cells, and genes. Humanized mice are basically employed in medical and biological therapeutics as animal models. Immunodeficient mouse are often act as recipients of tissues or human cells, as they can easily receive heterologous cells because of lack of immunity in the host.

Bioprocess technology forms the backbone of the biotechnology industry. In a bioprocess living cells such as bacteria, enzymes, and chloroplast or their components are used to procure desired products. The process is leveraged to develop industrial products, processes and techniques to fulfill the needs of society.

The global pharmaceutical membrane filtration market is expected to witness strong growth throughout the forecast period. The presence of a strong biologics pipeline and the growth potential in several developing economies are some of the major factors anticipated to fuel the growth of the overall market in the next few years. The research study has highlighted the anticipated growth rate and the shares of each segment in the global pharmaceutical membrane filtration market to offer a clear picture and detailed understanding.

Cellular analysis technology has wide applications in cell identification, target identification and validation, and cell counting. The technology is widely used in analysis of cell interaction, cell proliferation, cell structure, cell viability, and cell signaling/cell transduction. Prominent applications of cellular analysis include its uses in various phases of the drug discovery process, oncology, blood cell analysis, and toxicity testing.

The global market for in situ hybridization is projected to expand at a phenomenal rate, with the cancer diagnosis segment at the forefront. The in situ hybridization market can include application segments such as neuroscience, cancer diagnosis, immunology, cytology, microbiology, pathology, and developmental biology. 

Regulations for the security of life, well-being of plants and animals, human health, and environmental compliance will influence market players for increased focus on import, export, and commercialization of genetically modified organisms (GMOs).

Cell Cycle analysis is a highly demanded method for the evaluation of cells in the diverse phases of cell cycle. The determination of cellular response to a variety of drugs and biological stimulations is one of the trending elements prevailing in the global cell cycle analysis market. Most of the methods used during the analysis of cell cycle are based on florescence assays.

Genetic analyzers are complex equipment that contain instruments and chemical solutions needed to carry out the genetic analysis of a genome sample. Genetic analysis is extensive that involves DNA sequencing studies, DNA microarray studies, cytogenetic studies like karyotyping, DNA amplification and other processes. 

Nucleic acid, also known as DNA is the functional and fundamental component of the body cells. Nucleic acid comprises most of the vital information, which is essential in order to transfer the genetic information from one generation to another generation

Combi-chem or combinational chemistry is an innovative method of synthesizing multiple chemical compounds within a short turnaround time. Combinational chemistry is considered to be a less time-consuming and labor-intensive option to traditional chemistry, where compounds are synthesized one at a time.

Whole exome sequencing involves the sequencing of all protein-coding genes in a genome. Clinically exome account for 82% to 85% of known disease-causing variants and less than 1.5% to 2% of the human genome, which converts whole-exome sequencing into an effective alternative. 

With continued enhancement of new sequencing technology, next-generation sequencing (NGS) is being increasingly used in cancer genomics research. Also known as massively parallel sequencing, these days NGS is being leveraged in clinical oncology to provide improved tailored therapy for cancer.

Proteins have found application in the therapeutics industry for long and are much sought after in modern medicine too. This has resulted in a growing number of protein-based drugs in market these days. However, there are quite a few pressing problems associated with their use such as swift degradation and excretion from patients, requiring frequent dosing. 

The global immunohistochemistry market is poised to make a bold statement with an impressive growth rate on the back of its irreplaceable application in the detection of the expression of different cancer biomarkers, such as PD-L1, NGS, RBM4, and SASH1. 

The increasing investment in research and development of novel therapeutics owing to the rising incidence of chronic diseases has led to immense growth in the global stem cell assay market. In the next couple of years, the market is expected to spawn into a multi-billion dollar industry as healthcare sector and governments around the world increase their research spending.

Transfection is one of the key research efforts leading the studies in synthetic genetics. While transfections can result in the formation of abnormal cells and unpredictable morphologies, the process can also be used to study the formation of genetic make-up and to transform cell structures through their deliberate infection.